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Refresh Life Overview

Our mission is to expand the awareness of the ground breaking research that is transforming oral health as the key to brain health, heart health, and longevity.
Around the world, a silent epidemic is taking root in our mouths. Porphyromonas gingivalis (Pg) — a stealth bacterial pathogen — has emerged as one of the most dangerous threats to public health. Once it colonizes the gums, Pg releases toxins that enter the bloodstream and spread throughout the body. These toxins have been linked to Alzheimer’s disease, cardiovascular disease, diabetes, stroke, and even premature birth. Modern science now confirms that oral health is inseparable from brain and body health — and Pg sits at the center of this connection. Despite decades of dental hygiene advances, there has been no effective defense against Pg. It evades the body’s immune system, hides deep in dental plaque, and rapidly returns within days of a professional cleaning. Brushing and flossing alone cannot remove it. For millions, this means a lifetime of recurring oral infection that fuels chronic inflammation — the underlying driver of many degenerative diseases. This gap between what medicine knows and what current oral care can address represents one of the largest unmet medical needs of our time. At Refresh Life™, we believe the solution begins where disease begins — in the mouth. Our mission is to bridge oral and systemic health through next-generation science that helps eliminate Pg and restore balance to the oral microbiome. Founded by Dr. Dan Sindelar, a dentist and Alzheimer’s researcher with more than 35 years of clinical experience, Refresh Life Pro™ is built on breakthrough bio-active technology designed to protect the brain, heart, and longevity itself. Because true health starts with a healthy mouth.
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Nothing is Scarier than Pg in your Mouth

One bacterium, Porphyromonas gingivalis (Pg),
may link your mouth to Alzheimer’s, heart disease, and aging.
Pg releases Billions of Toxins everyday that can enter your bloodstream if left unchecked.

We’re changing that — with technology designed to neutralize Pg at its source.

 

🦷 Oral Health | 🧠 Brain Health | 💙 Longer Life

You can’t have a Healthy Mouth if you have Pg in it.

Pg toxins spread through the body, harming the brain, heart, and longevity.

Pg evades the body’s immune system to ensure its own survival.

Dental cleaning, flossing, and brushing can’t eliminate it —
we’ve never stood a chance… until now.

Oral Health Brain Health Longer Life

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Oral Health, Brain Health, Longer Life — It Starts Here

Introducing Refresh Life Pro™ — premium daily oral care for people pursuing cognitive, cardiovascular, and whole-body longevity.

Not just fresher breath. Not just whiter teeth.

True, deeper health — from the source.

Powered by cutting-edge science, our Dentaboost™ technology supports a balanced oral microbiome and reduces harmful biofilm including P. gingivalis, protecting your smile and your mind.

Health meets beauty.

Your new daily ritual for a longer, sharper, healthier life.

 All of my patients in their 80s and 90s living full, healthy lives had the gums of a 16 year old. – Dr Dan

Your oral microbiome impacts:

🧠 Brain aging

❤️ Heart health

🔥 Inflammation

🩸 Metabolic health

Health span

 Oral Health Brain Health Longer Life

Welcome to the era of oral longevity care.

The Future of Whole-Body Health Starts in the Mouth

Meet Refresh Life Pro™ — next-generation oral care designed to eliminate P. gingivalis, the most dangerous oral pathogen linked to inflammation, Alzheimer’s, cardiovascular disease, and systemic aging.

We protect the brain, heart, and longevity by starting where disease begins: your mouth.

35+ years in dentistry, 7+ years in Alzheimer’s research, and breakthrough bio-active technology — finally in a daily system anyone can use.

This is oral medicine for modern longevity.

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